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Natural killer cells – the body’s own patrol against viruses and tumours

Jan 17, 2013


Setting the stage for personalised medicine, researchers decode major immune cell's protein content

 

Scientists at the Helmholtz Centre for Infection Research (HZI) have analysed for the first time all the proteins inside natural killer (NK) cells of healthy individuals. The newly discovered “protein repertoire” shows that these immune cells cannot only defend us against acute viral infections but they can also store information about earlier infections. The researchers have identified new proteins that help to determine NK cell condition. These findings may improve the basis for personalized therapies.

Original Publication:

Maxi Scheiter, Ulrike Lau, Marco van Ham, Björn Bulitta, Lothar Gröbe, Henk Garritsen, Frank Klawonn, Sebastian König & Lothar Jänsch
Proteome Analysis of Distinct Developmental Stages of Human Natural Killer Cells
Molecular & Cellular Proteomics 2013

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